Understanding Tay-Sachs Disease Essay -- Human Diseases, Genetic Diso

IntroductionWhen presented with this assignment, infantile amaurotic idiocy illness was nonp beil of the first choices that came to mind since it is one of many diseases associated with Ashkenazi Jews (Jews of Eastern European descent). Tay-Sachs is a deadly transmissible disease caused by the absence or mutation of Hex- A, an enzyme that breaks down tortuous fats called gangliosides found in nervous tissue. Without Hex- A, there is a buildup of gangliosides in the cells of the brain, causation major damage to the cells (Learning About Tay-Sachs Disease). Tay-Sachs is an autosomal recessive genetic disarray, which means that both pargonnts must be a carrier of the diseased allele for the children to be at risk. The kindle thing about autosomal recessive disease allele is that they are hidden by the functionally normal allele and therefore preempt remain hidden for generations. Only when the couple has the same recessive disease allele there is a twenty-five percent chance tha t the disorder will appear in the child (Teichler-Zallen 162-163). Though there are three existing forms of Tay-Sachs disease (Classic (Infantile), Juvenile, and Late Onset Tay-Sachs), this news report will focus on the most common form, Classic (Infantile) Tay-Sachs. world-wide symptoms for all three forms include loss of motor skills, muscular weakness, and respiratory decline (Tay-Sachs Disease). This paper will give the reader brain wave into the history as well as a more slender description of the symptoms, diagnosis, and prevalence of the disease.HistoryIn the early 1880s, three partly blind infants were brought to a clinic in London supervised by an optometrist named Warren Tay. All three infants had the same symptoms they were unable to turn everywhere or sit up and they were unab... ...e.gov/10001220. Goldberg, Carey. First Human Gene Therapy endeavor Planned For Deadly Tay-Sachs Disease CommonHealth. CommonHealth Reform And Reality. 11 Nov. 2011. Web. 21 Nov. 201 1. . Tay-Sachs Disease CCJGD. Chicago Center for Jewish Genetic Disorders CCJGD. Web. 16 Nov. 2011. . Tay-Sachs Disease. NTSAD. National Tay-Sachs & Allied Diseases. Web. 16 Nov. 2011. . Teichler-Zallen, Doris. To Test or Not to Test a Guide to Genetic Screening and Risk. new-sprung(prenominal) Brunswick, NJ Rutgers UP, 2008. 162-63. Print. WHO Genes and Human Disease. Genomic Resource Centre. World Health Organization. Web. 16 Nov. 2011. .